Chirality

Scheme : left handed L and right handed D enantiomers of [Ru(TAP)2(pyridine)2]2+

Two main strategies are usually used to achieve optical resolution of Ru(II) complexes :

A new method has also been recently developped by von Zelewsky et al. which is based on a new class of ligands called CHIRAl GENerators ligands or CHIRAGEN [5]. These CHIRAGEN ligands are able to transfer their chirality to metal centers and, in this way, a predetermination of the absolute configuration L and D at the metal center can be reached.


[1] B. Bosnich, F. Dwyer, Aust. J. Chem., 1966, 19, 2229

[2] B. Patterson, F. Keene, Inorg. Chem., 1998, 37, 645-650

    J. Lacour, S. Torche-Haldimann, J. Jordy, C. Ginglinger and F. Favarger, Chem. Commun., 1998, 1733-1734

    T. Rutherford, O. Van Gijte, A. Kirsch-De Mesmaeker and F. Keene, Inorg. Chem., 1997, 36, 4465-4474

[3] D. Hesek, Y. Inoue, S. Everitt, H. Ishida, M. Kunieda, M. Drew, Chem. Commun., 1999, 403-404

[4] A. Baker, R. Morgan and T. Sterkas, J. Am. Chem. Soc., 1991, 113, 1411-1412

[5] U. Knof and A. von Zelewsky, Angew. Chem. Int. Ed., 1999, 38, 302-322


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