New 5-aminolevulinic acid derivatives for selective protoporphyrin IX production in cells

Yann Berger^a, Alain Greppi^a, Olivier Siri^a, Lucienne Juillerat*^b, Reinhard Neier*^a

Mail questions and comments to reinhard.neier@ich.unine.ch or yann.berger@ich.unine.ch

^{a Institute of Chemistry, Neuchātel University, av. de Bellevaux 51 , CH-2000 Neuchātel, Switzerland

^b Institute of Pathology, CHUV, Lausanne University, rue de
Bugnon 27, CH-1011 Lausanne, Switzerland

This poster can be found on the site http://www.unine.ch/chim/photobiology99/titre.html

Introduction

Synthesis

Synthesis of ALA-polyethylenglycol ester acids
Synthesis of ALA derivatives containing peptide

Results and discussion

Fluorescence measurement of PpIX induced by ALA-PEG
ester acids

Fluorescence measurement of PpIX induced by ALA
derivatives containing peptide

Conclusion

Acknowledgements

References

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